Pharmaceutical production scheduling software plans and sequences batch and campaign production in a cGMP plant, honouring the constraints that make pharma different: cleaning validation windows, hold-times, line clearance, equipment qualification, and quality-release timing. Bodhee does this as , rebuilding a feasible plan continuously as the plant and the lab change, rather than setting a plan weekly and patching it by hand.
Adaptive Scheduling · Pharmaceuticals
Pharmaceutical Production Scheduling
that keeps pace with the plant floor.
When QC clears a hold, a cleaning cycle overruns, or a campaign resequences, Bodhee rebuilds a feasible, constraint-respecting schedule in minutes across production, quality, and maintenance. Purpose-built for cGMP process manufacturing.
Bodhee is the Adaptive Scheduling product family from Neewee, built for cGMP batch plants. It rebuilds schedules against live constraints, alongside your MES, ERP, and LIMS.
The challenge
Why scheduling breaks in pharmaceutical plants.
Pharma production runs on constraints most planning tools never model. Each gap costs capacity, adds planner effort, and surfaces late.
01
QC holds stall the whole plant
A batch waits on release testing or an OOS investigation, and downstream campaigns slip. The production plan cannot see the lab, so the delay surfaces late.
02
Cleaning and changeover eat the calendar
Line clearance, cleaning validation, and product-to-product changeovers consume large blocks of staffed time, and legacy planning treats them as afterthoughts.
03
Campaign sequencing is a manual puzzle
Sequencing multi-product campaigns to minimise changeovers and honour hold-times is done by hand in spreadsheets, and it breaks the moment reality shifts.
04
Compliance work is invisible to the schedule
Documentation, line clearance, and in-process checks take real hours that never appear on the plan, so the plan is optimistic and the floor falls behind.
05
Production, QC, and maintenance plan apart
Three functions plan on separate schedules that cannot replan together, so conflicts appear late and teams reconcile plans instead of running batches.
How Bodhee solves it
One pharma plant, one live schedule across production, quality, and maintenance.
Bodhee holds production, quality, and maintenance on a single live model of your site, so an event in one function replans the others automatically.
One live model of your plant.
Production, quality, and maintenance share a single live model, so a change in one function replans the others automatically, not at the next planning meeting.
Rescheduling in minutes, not shifts.
AI agents watch the floor and the lab, classify events, and invoke the scheduling engine within minutes. Planners get an explainable, feasible plan instead of an overnight manual rebuild.
cGMP constraints, honoured by design.
Cleaning validation windows, hold-times, line clearance, campaign rules, and equipment qualification status are modelled as first-class constraints, not bolted on after the fact.
What it does for pharma
Scheduling built around how pharma plants actually run.
01
Campaign and changeover-aware sequencing
Fewer changeovers, more right-first-time runs.
- Sequence multi-product campaigns to cut changeover and cleaning
- Honour product-to-product and hold-time rules
- Respect equipment qualification and line-clearance status
02
QC-hold-aware replanning
The plan that finally sees the lab.
- Replan production around release testing and OOS investigations
- Sync QC analyst and instrument capacity with batch flow
- Surface release-timing risk before it slips delivery
03
Cleaning, validation, and indirect work, scheduled
The hidden hours, on the plan.
- Model cleaning validation and line-clearance windows explicitly
- Cluster maintenance into the fewest disruptive windows
- Account for documentation and in-process checks
04
Cross-functional resynchronisation
One event, one coordinated replan.
- Propagate events across production, quality, and maintenance
- Assess cross-functional impact before committing
- Configurable response modes, from advisory to automatic
Trust & compliance
Built for GxP-regulated production.
Bodhee runs alongside your validated MES, eBR, QMS, and LIMS, and provides the technical and documentary controls your validation team expects. Compliance is achieved by the validated system at your site, not by the software alone.
ISO/IEC 27001
Certified ISMS, whole-organisation scope
21 CFR Part 11
Audit-trail-aligned, closed system
EU GMP Annex 11
Audit-trail-aligned
GAMP 5
Category 4 configured product
Data integrity
ALCOA+, append-only audit trail
Access control
RBAC with SSO and SAML
Electronic signatures are not supported by design; they are executed in your systems of record such as MES, eBR, QMS, and LIMS. Cloud-infrastructure attestations are inherited from Google Cloud Platform, not claimed as our own.
Measurable outcomes
What Bodhee delivers in pharmaceutical plants.
Ranges observed across regulated process manufacturing deployments. Outcomes vary by plant complexity, data maturity, and integration scope.
0–15 pp
OEE improvement
across regulated process manufacturing deployments
0–25%
On-time delivery
from more reliable schedule execution
0–25%
Changeover efficiency
from campaign- and changeover-aware sequencing
0–80%
Planner scheduling effort
as manual rebuilds give way to agentic replanning
Hours → Minutesrescheduling cycle time+10–15%cross-functional capacity recovery−10–20%wip inventory
Bodhee runs live pharmaceutical and process manufacturing production today, across multiple sites and countries. Live deployments, not pilots.
Based on Neewee deployment observations in regulated process manufacturing.
Go deeper
Related to pharmaceutical scheduling.
Where Bodhee fits across your plant, and how it deploys.
Bodhee Production SchedulingThe production scheduling engine in depth.Bodhee Quality Control SchedulingSequence the lab so release keeps pace with production.Bodhee Maintenance SchedulingCluster maintenance into the fewest disruptive windows.How Bodhee worksEvent flow and the techniques behind the schedule.Trust CenterSecurity, data integrity, and GxP posture.Case studiesOutcomes from real process plants.
Frequently asked questions
Pharmaceutical production scheduling, answered.
The questions pharma planners, quality leads, and IT teams ask before a pilot.
01
Bodhee models cleaning validation, line clearance, and product-to-product changeovers as first-class constraints, then sequences campaigns to reduce them. Changeover and cleaning time appears on the schedule instead of being absorbed as hidden hours, so plans stay feasible and capacity stays visible.
Yes. Bodhee Quality Control Scheduling shares the same live model as production, so a release test, a retest, or an OOS investigation replans downstream production automatically. Release-timing risk surfaces early instead of when a campaign is already slipping.
Bodhee is audit-trail-aligned with 21 CFR Part 11 (closed system, Subpart B controls) and EU Annex 11, and ships as a GAMP 5 Category 4 configured product under shared validation responsibility. It provides data integrity (ALCOA+), an append-only audit trail, and role-based access control with SSO and .
Compliance is achieved by the validated system at your site, not by the software alone. Electronic signatures are not supported by design; they are executed in your systems of record such as , eBR, QMS, and . Full detail is on the Trust Center.
Bodhee deploys alongside your existing , , , and rather than replacing them. It reads orders, master data, quality results, and equipment status through an event-driven integration layer, and publishes schedules and recommendations back out. It integrates with systems such as SAP and Oracle.
A typical Bodhee deployment runs 16 to 24 weeks across three phases: assessment and roadmap, plant-specific configuration and integration, then a parallel run into go-live. Every release ships with regression evidence so your validation team can run a validation-impact assessment before promotion.
Traditional generates a plan and holds it until the next planning cycle, so it drifts the moment a QC hold, a cleaning overrun, or a campaign change hits the floor. Bodhee's continuously rebuilds a feasible plan that honours cGMP constraints as production and the lab change, in minutes, not at the next planning meeting.
Pricing is scoped to plant complexity, the number of sites, and integration breadth rather than a fixed per-seat list price. A typical engagement is deployment-based over 16 to 24 weeks. Request a demo for a scoped quote.
Ready to schedule your pharma plant as one?
A 30-minute tour of Bodhee for pharmaceutical production: the engine, the cross-functional layer, and how it fits your MES, ERP, and LIMS.